EGIS-9377

Chemical Name: 2-(Methylsulfanyl)-N-[2-(4-morpholinyl)ethyl]-8,9-dihydro-7H-thiopyrano[3,2-d][1,2,4]triazolo[1,5-a]pyrimidin-5-amine dihydrochloride
CAS No. 144430-52-4 (free base)
项目整合开发状态: Preclinical
项目研究机构: Egis (Originator)
合成路线:The title compound was prepared by condensation of 5-chloro-2-(methylsulfanyl)-8,9-dihydro-7H-thiopyrano[3,2-d]-1,2,4-triazolo[1,5-a]pyrimidine (I) with N-(2-aminoethyl)morpholine (II) in the presence of Et3N in refluxing isopropanol.