新产品编号:661785

Chemical Name: 3,9-Dibenzyl-1,5,7,11-tetrahydroxymethyl-6,12-diphenyl-3,9-diazapentacyclo[6.4.0.0(2,7).0(4,11).0(5,10)]dodecane
CAS No. 252671-48-0
项目整合开发状态: Biological Testing
项目研究机构: Novartis (Originator)
合成路线:Cyclocondensation of a mixture of benzylamine (I),ethyl propiolate (II) and benzaldehyde (III) in hot AcOH furnished dihydropyridine (IV).Photodimerization of this compound in a MeOH-THF solution gave rise to the cage dimer (V).Finally,reduction of the ester groups of (V) by means of LiAlH4 at low temperature produced the title tetraol compound.