Fenbufen, CL-82204, Lederfen, Cinopal
芬布芬Chemical Name: 4-(4-Biphenylyl)-4-oxobutyric acid
CAS No. 36330-85-5
项目整合开发状态: Launched-1976
项目研究机构: Wyeth Pharmaceuticals (Originator)
合成路线:By condensation of biphenyl (I) and succinic anhydride (II) in nitrobenzene,using AlCl3,as catalyst.
📌 参考资料/链接：
参考文献标题:Compositions containing substituted benzoylpropionic acids and method of use to treat inflammation and pain
文献作者:Tomeufeik,A.; et al.(American Cyanamid Co.)
参考来源:DE 2147111; FR 2107848; GB 1320076; US 3784701
📄 详细内容
合成路线:By condensation of biphenyl (I) and succinic anhydride (II) in nitrobenzene,using AlCl3,as catalyst.
参考文献标题:Fenbufen
文献作者:Castar,J.
参考来源:Drugs Fut 1976,1(1),21
合成路线:By condensation of biphenyl (I) and succinic anhydride (II) in nitrobenzene,using AlCl3,as catalyst.
参考文献标题:A simple procedure for the isolation of gamma-oxobenzenebutanoic acid derivatives: Application to the synthesis of fenbufen
文献作者:Acharyulu,P.V.R.; Raju,C.M.H.; Srinivas,C.
参考来源:Org Process Res Dev 2004,8(2),291
产品链接: CAS No. 36330-85-5››