SB-235863A, SB-235863

Chemical Name: 4,5alpha-Epoxy-3-methoxy-4',17-dimethyl-6,7-didehydropyrrolo[2',3':6,7]morphinan-5'-carboxylic acid isobutyl ester
CAS No. 177284-77-4 (monoHCl)
项目整合开发状态: Preclinical
项目研究机构: GlaxoSmithKline (Originator)
合成路线:The compound was prepared by condensation of dihydrocodeinone hydrochloride (I) with N-Benzyl-N-isopropyl-2-(phenylhydrazono)-3-oxobutyramide (II) in the presence of zinc dust and NaOAc in refluxing AcOH.

合成路线:The compound was prepared by condensation of dihydrocodeinone hydrochloride (I) with N-Benzyl-N-isopropyl-2-(phenylhydrazono)-3-oxobutyric acid isobutyl ester (II) (II) in the presence of zinc dust and NaOAc in refluxing AcOH.