NNC-92-1687
Chemical Name: 2-(1H-Benzimidazol-2-ylsulfanyl)-1-(3,4-dihydroxyphenyl)-1-ethanone
CAS No. 22903-37-3, 22903-39-5 (monoHCl)
项目整合开发状态: Biological Testing
项目研究机构: Novo Nordisk (Originator)
合成路线:Title compound was synthesized by S-alkylation of 2-mercaptobenzimidazole (II) with a-chloro-3,4-dihydroxyacetophenone (I) in refluxing acetonitrile.
📌 参考资料/链接：
参考文献标题:Discovery and structure-activity relationship of the first non-peptide competitive human glucagon receptor antagonists
文献作者:Madsen,P.; Knudsen,L.B.; Wiberg,F.C.; Carr,R.D.
参考来源:J Med Chem 1998,41(26),5150