DR-4004
Chemical Name: 2a-[4-(4-Phenyl-1,2,3,6-tetrahydropyridin-1-yl)butyl]-1,2,2a,3,4,5-hexahydrobenz[cd]indol-2-one
CAS No. 201608-41-5
项目整合开发状态: Preclinical
项目研究机构: Meiji Seika (Originator)
合成路线:Tetrahydrobenzindole (I) was alkylated with 1,4-dibromobutane (II) in the presence of NaH to afford the bromobutyl derivative (III).This was then condensed with 4-phenyltetrahydropyridine (IV) to yield the title compound.
📌 参考资料/链接:
参考文献标题:Tetrahydrobenzindoles: Selective antagonists of the 5-HT7 receptor
文献作者:Kikuchi,C.; Nagaso,H.; Hiranuma,T.; Koyama,M.
参考来源:J Med Chem 1999,42(4),533