N-5228

Chemical Name: trans-(all E)-N,N'-Bis(3,4-dimethoxybenzyl)-N-(3,7,11,15,19,23,27,31,35-nonamethyl-2,6,10,14,18,22,26,30,34-hexatriacontanonaenyl)cyclohexane-1,2-diamine
CAS No. 194720-56-4, 194721-15-8 (as dihydrochloride), 194720-58-6 (cis-isomer), 194720-64-4 (R,R), 194720-65-5 (S,S)
项目整合开发状态: Biological Testing
项目研究机构: Nisshin Pharma (Originator)
合成路线:Reductive alkylation of trans-1,2-cyclohexanediamine (I) with veratraldehyde (II) in the presence of NaBH4 afforded the corresponding bis-(benzylamino)cyclohexane derivative (III).This was then alkylated with solanesyl bromide (IV) in THF to furnish the title compound