新产品编号:242555
Chemical Name: N,N',N'',N'''-(1,4,8,11-Tetraazacyclotetradecan-1,4,8,11-tetrayl)tetrakis(pentane-1,5-diyl)tetrakis(N-benzylcarbamic acid tert-butyl ester)
CAS No. 192518-27-7
项目整合开发状态: Biological Testing
项目研究机构: INSERM (Originator)
合成路线:The title compound was obtained by alkylation of tetraazacyclo tetradecane (I) with an excess of tosylate (II) in the presence of K2CO3 in refluxing acetonitrile.
📌 参考资料/链接：
参考文献标题:Design,synthesis and structure relationships of new N,N',N'',N'''-tetrakis (omega-amino alkyl) tetraazamacrocycles
文献作者:Trabaud,C.; Dessolin,J.; Camplo,M.; Hantz,O.; Zoulim,F.; Borel,C.; Meyer,M.; Pepe,G.; Chermann,J.-C.; Kraus,J.-L.
参考来源:Antivir Chem Chemother 1998,9(1),73-84
📄 详细内容
合成路线:The title compound was obtained by alkylation of tetraazacyclo tetradecane (I) with an excess of tosylate (II) in the presence of K2CO3 in refluxing acetonitrile.
参考文献标题:Modelisation,synthesis and anti-HIV activities of N,N,N',N'',N'''-pentakistetraazamacrocycles salts derivatives
文献作者:Chermann,J.C.; Dessolin,J.; Bouygues,M.; Trabaud,C.; Kraus,J.L.; Vieghe,P.; Camplo,M.
参考来源:Bioorg Med Chem Lett 1997,7(10),1353