OPB-9195
Chemical Name: (?-2-(Isopropylidenehydrazono)-5-[N-(phenyl)carbamoylmethyl]thiazolidin-4-one
CAS No. 163107-50-4
项目整合开发状态: Preclinical
项目研究机构: Otsuka (Originator)
合成路线:The title amide was prepared by coupling of the previously reported 5-carboxymethyl-2-isopropylidenehydrazonothiazolidin-4-one (I) with aniline (II) in the presence of EDC and HOBt.
📌 参考资料/链接：
参考文献标题:Thiazole or imidazole derivs.as Maillard reaction inhibitors
文献作者:Yasumura,K.; Miyajima,K.; Nagahama,T.; Ishikawa,S.; Tohyama,Y.; Sugiyama,K.(Otsuka Pharmaceutical Co.,Ltd.)
参考来源:EP 0638075; JP 1995133264; JP 1998167965; WO 9419335