MRS-1704
Chemical Name: 2,6-Dimethyl-4-phenyl-4H-pyran-3,5-dicarboxylic acid diethyl ester
CAS No. 21299-05-8
项目整合开发状态: Biological Testing
项目研究机构: Bayer (Originator)
合成路线:The target compound can be obtained by heating benzaldehyde (I) with ethyl acetoacetate (II) in HOAc in the presence of ZnCl2 and Ac2O.
📌 参考资料/链接：
参考文献标题:Substd.4H-pyrans with a modulating effect on potassium channels
文献作者:Urbahns,K.; Heine,H.-G.; Junge,B.; Mauler,F.; Glaser,T.; Wittka,R.; De Vry,J.-M.-V.(Bayer AG)
参考来源:CA 2183048; DE 19529858; EP 0758648; JP 1997059271; US 5760073
📄 详细内容
合成路线:The target compound can be obtained by heating benzaldehyde (I) with ethyl acetoacetate (II) in HOAc in the presence of ZnCl2 and Ac2O.
参考文献标题:Pyran template approach to the design of novel A3 adenosine receptor antagonists
文献作者:Jacobson,K.A.; Li,A.H.; Ji,X.-D.; Melman,N.; Kim,H.S.
参考来源:Drug Dev Res 1999,48(4),171