RPR-101511A

Chemical Name: 6,7-Dimethoxy-2-(3-thienyl)quinoxaline hydrochloride
CAS No. 146847-57-6
项目整合开发状态: Preclinical
项目研究机构: Aventis Pharma (Originator)
合成路线:Oxidation of 3-acetylthiophene (I) with selenium dioxide in refluxing dioxan provided 3-thienylglyoxaldehyde hydrate (II).This was then condensed with 4,5-dimethoxy-1,2-phenylenediamine (III) in boiling EtOH to produce the target quinoxaline,which was finally isolated as the hydrochloride salt.