合成路线:Oxidation of an aqueous solution of sodium 2-mercaptoethanesulfonate (I) with I2 provided the title disulfide.In a related procedure,addition of sodium hydrosulfide to the sodium salt of vinylsulfonic acid (II) gave intermediate (III) which,without isolation,was oxidized with O2 at 60 C under pressure.
参考文献标题:Reducing toxic effects of carboplatin using dithioethers
文献作者:Hausheer,F.H.; Seetharamulu,P.; Murali,D.; Reddy,D.G.; Haridas,K.(BioNumerik Pharmaceuticals,Inc.)
参考来源:WO 9811898
合成路线:Oxidation of an aqueous solution of sodium 2-mercaptoethanesulfonate (I) with I2 provided the title disulfide.In a related procedure,addition of sodium hydrosulfide to the sodium salt of vinylsulfonic acid (II) gave intermediate (III) which,without isolation,was oxidized with O2 at 60 C under pressure.
参考文献标题:Process for making mesna,dimesna and derivs.thereof
文献作者:Haridas,K.(BioNumerik Pharmaceuticals,Inc.)
参考来源:US 5808140; WO 9814426
合成路线:Oxidation of an aqueous solution of sodium 2-mercaptoethanesulfonate (I) with I2 provided the title disulfide.In a related procedure,addition of sodium hydrosulfide to the sodium salt of vinylsulfonic acid (II) gave intermediate (III) which,without isolation,was oxidized with O2 at 60 C under pressure.
参考文献标题:Coviracil NDA accepted for filing by FDA
文献作者:
参考来源:J Org Chem 1961,261330-1331
产品链接: CAS No. 16208-51-8››