SM-3163
Chemical Name: 3-[(1,5-Diphenylpentyl)oxy]-N,N-dimethyl-1-propanamine citrate
CAS No. 77334-62-4 (ethanedioate (1:1))
项目整合开发状态: Phase II
项目研究机构: Sumitomo Pharmaceuticals (Originator)
合成路线:By condensation of 1,5-diphenyl-1-pentanol (I) with 3-(dimethylamino)propyl chloride (II) by means of NaH in refluxing toluene,followed by a treatment with citric acid.
📌 参考资料/链接：
参考文献标题:Diphenylalkanoether and diphenylalkanone oximeether derivatives
文献作者:Ono,K.; Kawakami,H.; Katsube,J.(Sumitomo Pharmaceuticals Co.,Ltd.)
参考来源:EP 0017217; US 4388469; US 4426394; US 4482573; US 4620036
📄 详细内容
合成路线:By condensation of 1,5-diphenyl-1-pentanol (I) with 3-(dimethylamino)propyl chloride (II) by means of NaH in refluxing toluene,followed by a treatment with citric acid.
参考文献标题:SM-3163
文献作者:Castar,J.; Prous,J.
参考来源:Drugs Fut 1986,11(12),1046