Ro-22-6923, Ro-226923
Chemical Name: (5Z,11alpha,13E,15R)-15-(Acetyloxy)-11,16,16-tri- methyl-9-oxoprosta-5,13-dien-1-oic acid
CAS No. 81397-66-2
项目整合开发状态: Biological Testing
项目研究机构: Alcon (Originator), Roche (Originator)
合成路线:By acetylation of 15-hydroxy-11,16,16-trimethyl-9-oxoprosta-5,13-dienoic acid (I) with acetic anhydride and 4-(dimethylamino)pyridine-triethylamine at room temperature.
📌 参考资料/链接：
参考文献标题:15-Acetyl-prostaglandins
文献作者:Holland,G.W.; Rosen,P.; Gallo-Torres,H.(F.Hoffmann-La Roche AG)
参考来源:EP 0049853; JP 57093956; US 4325970
📄 详细内容
合成路线:By acetylation of 15-hydroxy-11,16,16-trimethyl-9-oxoprosta-5,13-dienoic acid (I) with acetic anhydride and 4-(dimethylamino)pyridine-triethylamine at room temperature.
参考文献标题:RO-226923
文献作者:Pento,J.T.; Castar,J.; Serradell,M.N.
参考来源:Drugs Fut 1986,11(2),123