Brovincamine fumarate, Sabromin
溴长春胺Chemical Name: (3alpha,14beta,16alpha)-11-Bromo-14,15-dihydro-14-hydroxyeburnamenine-14-carboxylic acid methyl ester fumarate; (12S,13aS,13bS)-9-Bromo-13a-ethyl-12-hydroxy-2,3,5,6,12,13,13a,13b-octahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylic acid methyl ester fumarate
CAS No. 57475-17-9 (free base)
项目整合开发状态: Launched-1986
项目研究机构: Novartis (Originator), Sankyo (Licensee)
合成路线:By bromination of vincamine (I) with Br2 in CHCl3 using FeCl3 as catalyst.
📌 参考资料/链接：
参考文献标题:Substituted 5-(2-imidazolin-2-yl)aminopyrimidines
文献作者:Fleck,W.; Stenzel,W.; Armah,B.; Cohnen,E.(Beiersdorf-Lilly GmbH)
参考来源:DE 2849537; JP 1980092383
📄 详细内容
合成路线:By bromination of vincamine (I) with Br2 in CHCl3 using FeCl3 as catalyst.
参考文献标题:Brovincamine fumarate
文献作者:Prous,J.; Castar,J.
参考来源:Drugs Fut 1987,12(4),329
产品链接: CAS No. 57475-17-9››