Apovincamine

长春西汀杂质BChemical Name: (13aR*,13bR*)-13a-Ethyl-2,3,5,6,13a,13b-hexahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij]-1,5-naphthyridine-12-carboxylic acid methyl ester
CAS No. 4880-92-6
项目整合开发状态: Not Determined
项目研究机构:
合成路线:By dehydration of vincamine (I) with H2SO4 in methylene chloride (1,2),with refluxing 85% formic acid (3),with hot acetic anhydride (4),or other dehydrating agents (5,6).
📌 参考资料/链接:
参考文献标题:
文献作者:Kisfaludy,L.; et al.
参考来源:CA 965791; CA 968355; CH 530993; DE 1958514; FR 2023918; GB 1252618; JP 7038704; NL 6917604

📄 详细内容


合成路线:By dehydration of vincamine (I) with H2SO4 in methylene chloride (1,2),with refluxing 85% formic acid (3),with hot acetic anhydride (4),or other dehydrating agents (5,6).

参考文献标题:
文献作者:Kisfaludy,L.; et al.
参考来源:HU 2849


合成路线:By dehydration of vincamine (I) with H2SO4 in methylene chloride (1,2),with refluxing 85% formic acid (3),with hot acetic anhydride (4),or other dehydrating agents (5,6).

参考文献标题:
文献作者:
参考来源:NL 302131


合成路线:By dehydration of vincamine (I) with H2SO4 in methylene chloride (1,2),with refluxing 85% formic acid (3),with hot acetic anhydride (4),or other dehydrating agents (5,6).

参考文献标题:
文献作者:Clauder,O.; et al.
参考来源:HU 151295


合成路线:By dehydration of vincamine (I) with H2SO4 in methylene chloride (1,2),with refluxing 85% formic acid (3),with hot acetic anhydride (4),or other dehydrating agents (5,6).

参考文献标题:Alkaloids.IX.Structure of vincamine
文献作者:Trojanek,J.; et al.
参考来源:Coll Czech Chem Commun 1964,29(2),433-446


合成路线:By dehydration of vincamine (I) with H2SO4 in methylene chloride (1,2),with refluxing 85% formic acid (3),with hot acetic anhydride (4),or other dehydrating agents (5,6).

参考文献标题:The constitution of vincamine
文献作者:Mokry,J.; et al.
参考来源:Chem Zvesti 1962,16140-150


合成路线:By dehydration of vincamine (I) with H2SO4 in methylene chloride (1,2),with refluxing 85% formic acid (3),with hot acetic anhydride (4),or other dehydrating agents (5,6).
参考文献标题:Apovincamine
文献作者:Blancafort,P.; Serradell,M.N.; Castar,J.; de Angelis,L.
参考来源:Drugs Fut 1980,5(3),118


产品链接: CAS No. 4880-92-6››