Sulmazole, AR-L-115-BS
苏马佐Chemical Name: 2-[2-Methoxy-4-(methylsulfinyl)phenyl]-1H-imidazo[4,5-b]pyridine
CAS No. 73384-60-8, 53930-42-0 (mono HCl salt)
项目整合开发状态: Biological Testing
项目研究机构:
合成路线:2,3-Pyridiamine (I) is cyclized with 2-methoxy-4-methylmercaptobenzoic acid (II) in the presence of POCl3 to give (III),which is oxidized to AR-L-115-BS by hydrogen peroxide.(1,2)
📌 参考资料/链接：
参考文献标题:Sulmazole
文献作者:Unterhalt,B.
参考来源:Drugs Fut 1981,6(7),421
📄 详细内容
合成路线:2,3-Pyridiamine (I) is cyclized with 2-methoxy-4-methylmercaptobenzoic acid (II) in the presence of POCl3 to give (III),which is oxidized to AR-L-115-BS by hydrogen peroxide.(1,2)
参考文献标题:Radio-Synthese von (14C)-[(2-Methoxy-4-methylsulfinyl)phenyl]-1H-imidazo[4,5-b]pyridin (AR-L 115 BS)
文献作者:Zipp,H.; et al.
参考来源:Arzneim-Forsch Drug Res 1981,31(5),200
合成路线:2,3-Pyridiamine (I) is cyclized with 2-methoxy-4-methylmercaptobenzoic acid (II) in the presence of POCl3 to give (III),which is oxidized to AR-L-115-BS by hydrogen peroxide.(1,2)
参考文献标题:
文献作者:Kutter,E.; et al.(Dr.Karl Thomae GmbH)
参考来源:AU 332873; DE 2305339; FR 2215968; GB 1445824; JP 74102693; NL 7401254; US 3985891; ZA 7400695
产品链接: CAS No. 73384-60-8›› 产品链接: CAS No.53930-42-0››