Fenretinide, NSC-374551, McN-R-1967, HPR, 4-HPR
芬维A胺Chemical Name: N-(4-Hydroxyphenyl)-all-trans-retinamide
CAS No. 65646-68-6
项目整合开发状态: Phase III
项目研究机构: National Cancer Institute (Originator), R.W. Johnson (Originator)
合成路线:The reaction of retinoic acid (I) with PCl3 in dry benzene gives the corresponding retinoyl chloride (II),which is then condensed with 4-aminophenol (III) in DMF - ether.
📌 参考资料/链接：
参考文献标题:4-Hydroxyphenylretinamide
文献作者:Hillier,K.; Blancafort,P.; Serradell,M.N.; Castar,J.
参考来源:Drugs Fut 1980,5(3),132
📄 详细内容
合成路线:The reaction of retinoic acid (I) with PCl3 in dry benzene gives the corresponding retinoyl chloride (II),which is then condensed with 4-aminophenol (III) in DMF - ether.
参考文献标题:Esters of retinoic acid
文献作者:Gander,R.J.; Gurney,J.A.
参考来源:BE 0847942; CA 1062700; GB 1543824; NL 7612201; US 4108880
产品链接: CAS No. 65646-68-6››