网站主页>>>
项目整合精选>>>
项目整合精选>>>Foscarnet sodium, EHB-776, PFA, A-29622, Triapten, Virudin, Foscavir
Foscarnet sodium, EHB-776, PFA, A-29622, Triapten, Virudin, Foscavir
膦甲酸钠Chemical Name: Phosphonoformic acid trisodium salt; Trisodium carboxyphosphate; Trisodium phosphonoformate; Dihydroxyphosphinecarboxylic acid oxide trisodium salt
CAS No. 63585-09-1
项目整合开发状态: Launched-1989
项目研究机构: AstraZeneca (Originator), Wyeth Pharmaceuticals (Not Determined), Bracco (Licensee), Merck & Co. (Licensee)
合成路线:The reduction of triethyl phosphite (I) with ethyl chloroformate (II) gives phosphonoformic acid triethyl ester (III),which is hydrolyzed with refluxing aqueous NaOH.Other alkyl esters can be used instead.
📌 参考资料/链接：
参考文献标题:Foscarnet sodium
文献作者:Castar,J.; Blancafort,P.; Hopkins,S.J.; Serradell,M.N.
参考来源:Drugs Fut 1980,5(7),345
📄 详细内容
合成路线:The reduction of triethyl phosphite (I) with ethyl chloroformate (II) gives phosphonoformic acid triethyl ester (III),which is hydrolyzed with refluxing aqueous NaOH.Other alkyl esters can be used instead.
参考文献标题:Carboxyphosphonates
文献作者:McIntosh,C.L.
参考来源:US 4018854
合成路线:The reduction of triethyl phosphite (I) with ethyl chloroformate (II) gives phosphonoformic acid triethyl ester (III),which is hydrolyzed with refluxing aqueous NaOH.Other alkyl esters can be used instead.
参考文献标题:Carboxyphosphonate brush control agents
文献作者:McIntosh,C.L.
参考来源:US 4042650
产品链接: CAS No. 63585-09-1››