Miriplatin, SMP-11355, SM-11355, DACHPM, DACHPt(II)(Myr)2

米铂Chemical Name: (SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kappaN,kappaN'])bis(myristato-kappaO)platinum(II)
CAS No. 141977-79-9
项目整合开发状态: Phase II
项目研究机构: Sumitomo Pharmaceuticals (Originator)
合成路线:Dichlorocyclohexane-1,2-diamine platinum complex (II) was prepared from (R,R)-1,2-cyclohexanediamine (I) according to a known method.Subsequent treatment of (II) with aqueous silver nitrate produced the diaqua complex (III).Finally,displacement of H2O by means of sodium myristate (IV) gave rise to the title compound.