Pilsicainide hydrochloride, DU-6552, SUN-1165, Sunrythm
盐酸吡西卡呢 吡西卡尼 Chemical Name: N-(2,6-Dimethylphenyl)-8-pyrrolizidineacetamide hydrochloride; N-(2,6-Dimethylphenyl)-1-azabicyclo[3.3.0]octane-5-acetamide hydrochloride
CAS No. 88069-49-2, 88069-67-4 (free base)
项目整合开发状态: Launched-1991
项目研究机构: Daiichi Suntory Pharma (Originator), Daiichi Pharmaceutical (Licensee)
合成路线:By condensation of 2,6-dimethylaniline (I) with 8-pyrrolizineacetlc acid (II) by means of NaH in refluxing dioxane.
📌 参考资料/链接：
参考文献标题:8-(Substituted-N-phenylcarboxamidomethyl)pyrrolizidines and use thereof as antiarrhythmics
文献作者:Miyano,S.; Sumoto,K.; Morita,M.; Sato,F.(Suntory Ltd.)
参考来源:EP 0089061; JP 58159793; US 4564624
📄 详细内容
合成路线:By condensation of 2,6-dimethylaniline (I) with 8-pyrrolizineacetlc acid (II) by means of NaH in refluxing dioxane.
参考文献标题:SUN-1165
文献作者:Thorpe,P.J.; Serradell,M.N.; Castar,J.
参考来源:Drugs Fut 1985,10(6),483
产品链接: CAS No. 88069-49-2›› 产品链接: CAS No.88069-67-4››