合成路线:The condensation of beta-phenyl-2-hydroxypropiophenone sodium salt (I) with 1-chloro-2,3-epoxypropane (A) at 100 C yields beta-phenyl-2-(2',3'-epoxypropoxy)propiophenone (II).which is then treated with n-propylamine (B) also at 100 C.
参考文献标题:Zur Pharmakologie von 2'-[2-Hydroxy-3-(propylamino).propoxy]-3-phenylpropiophenon (Propafenon,SA79)-hydrochlorid
文献作者:Prigge,E.; Hapke,H.J.
参考来源:Arzneim-Forsch Drug Res 1976,36(10),1849-57
合成路线:The condensation of beta-phenyl-2-hydroxypropiophenone sodium salt (I) with 1-chloro-2,3-epoxypropane (A) at 100 C yields beta-phenyl-2-(2',3'-epoxypropoxy)propiophenone (II).which is then treated with n-propylamine (B) also at 100 C.
参考文献标题:2-Hydroxy-3-phenylpropiophenone derivatives
文献作者:Sauchse,R.
参考来源:AT 308076B; BE 0785318; DE 2001431; FR 2144601; GB 1307455; NL 7208214
合成路线:The condensation of beta-phenyl-2-hydroxypropiophenone sodium salt (I) with 1-chloro-2,3-epoxypropane (A) at 100 C yields beta-phenyl-2-(2',3'-epoxypropoxy)propiophenone (II).which is then treated with n-propylamine (B) also at 100 C.
参考文献标题:Einflu?des antiarrhythmikus propafenon auf die intrakardiale erregungsleitung
文献作者:Beck,O.A.; et al.
参考来源:Z Kardiol 1975,64731-740
产品链接: CAS No. 34183-22-7›› 产品链接: CAS No.54063-53-5››