Meclofenamate sodium, CI-853(free acid), Meclodol, Meclomen
甲氯芬那酸钠 甲氯芬那酸 Chemical Name: 2-(2,6-Dichloro-3-methylphenylamino)benzoic acid sodium salt hydrate
CAS No. 6385-02-0, 644-62-2 (free acid)
项目整合开发状态: Launched-1980
项目研究机构: Pfizer (Originator)
合成路线:By condensation of o-bromobenzoic acid (I) with 2,6-dichloro-3-methylaniline (II) by means of CuBr2 in diethylene glycol dimethyl ether containing N-ethylmorpholine and heated at 145-55 C.
📌 参考资料/链接：
参考文献标题:Meclofenamic acid
文献作者:Arrigoni-Martelli,E.; Castar,J.
参考来源:Drugs Fut 1978,3(4),307
📄 详细内容
合成路线:By condensation of o-bromobenzoic acid (I) with 2,6-dichloro-3-methylaniline (II) by means of CuBr2 in diethylene glycol dimethyl ether containing N-ethylmorpholine and heated at 145-55 C.
参考文献标题:Anthranilic acids and derivatives
文献作者:Scherrer,R.A.; Short,F.W.
参考来源:US 3313848
产品链接: CAS No. 6385-02-0›› 产品链接: CAS No.644-62-2››