Moxipraquine, 349-C-59
甲氧丙喹Chemical Name: 4-[4-[6-(6-Methoxyquinolin-8-ylamino)hexyl]piperazin-1-yl]butan-2-ol
CAS No. 23790-08-1, 23790-07-0 (triHCl)
项目整合开发状态: Biological Testing
项目研究机构:
合成路线:The reaction of 8-(6-bromocaproamido)-6-methoxyquinoline (I) with N-(3-hydroxy-n-butyl)piperazine (II) by means of triethylamine in refluxing benzene gives 8-[6-[4-(3-hydroxy-n-butyl)piperazin-1-yl]-1-oxohexylamino]-6-methoxyquinoline (III),which is reduced with LiAlH4 in refluxing THF
📌 参考资料/链接：
参考文献标题:Moxipraquine
文献作者:Blancafort,P.; Serradell,M.N.; Castar,J.; Hillier,K.
参考来源:Drugs Fut 1981,6(6),356
📄 详细内容
合成路线:The reaction of 8-(6-bromocaproamido)-6-methoxyquinoline (I) with N-(3-hydroxy-n-butyl)piperazine (II) by means of triethylamine in refluxing benzene gives 8-[6-[4-(3-hydroxy-n-butyl)piperazin-1-yl]-1-oxohexylamino]-6-methoxyquinoline (III),which is reduced with LiAlH4 in refluxing THF
参考文献标题:
文献作者:Wall,L.P.(Wellcome Foundation,Ltd.)
参考来源:GB 1153471
产品链接: CAS No. 23790-08-1››