Butoctamide hemisuccinate, Listomin
琥珀酸氢布酰胺Chemical Name: N-(2-Ethylhexyl)-3-hydroxybutyramide hydrogen succinate; N-2-Ethylhexyl-beta-hydroxybutyramide hydrogen succinate; N-(2-Ethylhexyl)-3-hydroxybutanamide hydrogen succinate
CAS No. 32838-28-1
项目整合开发状态: Launched-1985
项目研究机构: Banyu (Originator), Merck & Co. (Originator)
合成路线:The reaction of diketene (I) with 2-ethylhexylamine (II) gives N-(2-ethylhexyl)acetoacetamide (III),which is reduced to the target compound with H2 over Raney-Ni in methanol.
📌 参考资料/链接:
参考文献标题:N-Substd.-beta-oxybutyramide semisuccinate and its salt having effects of increasing paradoxical sleep and tranquillizing
文献作者:Yamagisawa,I.; Torii,S.; Sakuma,A.(Lion Corp.)
参考来源:DE 1768445; US 3639457