Loxiglumide, CR-1505, Loxizin
氯谷胺Chemical Name: (?-4-(3,4-Dichlorobenzamido)-N-(3-methoxypropyl)-N-phenylglutaramic acid; (?-4-(3,4-Dichlorobenzamido)-5-[N-(3-methoxypropyl)pentylamino)-5-oxopentanoic acid
CAS No. 107097-80-3
项目整合开发状态: Discontinued
项目研究机构: Rotta (Originator), Mitsubishi Pharma (Licensee), Kaken (Codevelopment)
合成路线:By condensation of N-(3,4-dichlorobenzoyl)-glutamic acid anhydride (I) with N-(3-methoxypropyl)-N-pentylamine (II) in water at 5 C.
📌 参考资料/链接：
参考文献标题:Pharmaceutically active derivatives of glutamic and aspartic acids
文献作者:Makovec,F.; Chist? R.; Rovati,C.L.; Rovati,A.L.(Rotta Research Laboratorium SpA)
参考来源:WO 8703869
📄 详细内容
合成路线:By condensation of N-(3,4-dichlorobenzoyl)-glutamic acid anhydride (I) with N-(3-methoxypropyl)-N-pentylamine (II) in water at 5 C.
参考文献标题:LOXIGLUMIDE
文献作者:Patoia,L.; Prous,J.; Castar,J.
参考来源:Drugs Fut 1990,15(1),32
产品链接: CAS No. 107097-80-3››