Loreclezole, R-72063
氯瑞唑Chemical Name: (Z)-1-(alpha,2,4-Trichlorostyryl)-1H-1,2,4-triazole; (Z)-1-[2-Chloro-2-(2,4-dichlorophenyl)vinyl]-1H-1,2,4-triazole
CAS No. 117857-45-1
项目整合开发状态: Phase II
项目研究机构: Janssen (Originator)
合成路线:By halogenation of 1-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-yl)ethanone (I) with refluxing phosphorus pentachloride.
📌 参考资料/链接：
参考文献标题:1-(2-Aryl-2-halo-1-ethenyl)-1H-azoles
文献作者:Heeres,J.(Janssen Pharmaceutica NV)
参考来源:EP 0142190; JP 1985166666; US 4539325
📄 详细内容
合成路线:By halogenation of 1-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-yl)ethanone (I) with refluxing phosphorus pentachloride.
参考文献标题:Loreclezole
文献作者:Castar,J.; Prous,J.
参考来源:Drugs Fut 1991,16(4),317
产品链接: CAS No. 117857-45-1››