Cloxacepride
氯沙必利Chemical Name: 5-Chloro-4-[[(4-chlorophenoxy)acetyl]amino]-N-[2-(diethylamino)ethyl]-2-methoxybenzamide; 5-Chloro-4-[2-(p-chlorophenoxy)acetamido]-N-[2-(diethylamino)ethyl]-o-anisamide; 5-Chloro-4-[2-(4-chlorophenoxy)acetamido]-N-[2-(diethylamino)ethyl]-2-methoxybenzamide
CAS No. 65569-29-1
项目整合开发状态: Phase II
项目研究机构: Merckle (Originator)
合成路线:By acylation of metoclopramide (I) with 2-(4-chlorophenoxy)acetic acid (II) by means of POCl3 in refluxing chloroform.
📌 参考资料/链接：
参考文献标题:Cloxacepride
文献作者:Serradell,M.N.; Castar,J.
参考来源:Drugs Fut 1984,9(5),322
📄 详细内容
合成路线:By acylation of metoclopramide (I) with 2-(4-chlorophenoxy)acetic acid (II) by means of POCl3 in refluxing chloroform.
参考文献标题:Cloxacepride and related compounds: A new series of orally active antiallergic compounds
文献作者:Metz,G.; Pindell,M.H.; Chen,H.L.
参考来源:J Med Chem 1983,26(7),1065-70
合成路线:By acylation of metoclopramide (I) with 2-(4-chlorophenoxy)acetic acid (II) by means of POCl3 in refluxing chloroform.
参考文献标题:Anti-inlammatory N-acyl substituted benzamides
文献作者:Metz,G.; Specker,M.
参考来源:BE 0854683; CH 633259; DE 2623228; FR 2352791; GB 1555723; US 4146637
产品链接: CAS No. 65569-29-1››