Cyanidin chloride monohydrate, IdB-1027, Gastrotelos
氯化矢车菊素Chemical Name: 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-1-benzopyrylium chloride monohydrate; 3,3',4',5,7-Pentahydroxyflavylium chloride monohydrate
CAS No. 528-58-5 (anhydrous)
项目整合开发状态: Phase II
项目研究机构: Inverni della Beffa (Originator)
合成路线:Condensation of 2,4-di-O-benzoylphloroglucinaldehyde (I) with omega-acetoxy-3,4-diacetoxyacetophenone (II) in the presence of HCl gives the 5,7-dibenzoyloxy-3-hydroxy-2-(3,4-dihydroxyphenyl)-1-benzopyrylium chloride (III),which is subsequently hydrolyzed with NaOH and finally treated with HCl.
📌 参考资料/链接：
参考文献标题:Process for the synthesis of anthocyanidines and novel intermediates produced in said processes
文献作者:Gabetta,B.; Giorgi,R.; Pifferi,G.(Incyte Pharmaceuticals,Inc.)
参考来源:EP 0348121; ES 2053992T; JP 2040376; PT 90920
📄 详细内容
合成路线:Condensation of 2,4-di-O-benzoylphloroglucinaldehyde (I) with omega-acetoxy-3,4-diacetoxyacetophenone (II) in the presence of HCl gives the 5,7-dibenzoyloxy-3-hydroxy-2-(3,4-dihydroxyphenyl)-1-benzopyrylium chloride (III),which is subsequently hydrolyzed with NaOH and finally treated with HCl.
参考文献标题:IdB-1027
文献作者:Magistretti,M.J.; Pifferi,G.
参考来源:Drugs Fut 1989,14(3),224
产品链接: CAS No. 528-58-5››