Fluprofylline, Sgd-14480
氟丙茶碱Chemical Name: 7-[3-[4-(4-Fluorobenzoyl)piperidin-1-yl]propyl]theophylline; 7-[3-[4-(4-Fluorobenzoyl)piperidin-1-yl]propyl]-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione
CAS No. 85118-43-0
项目整合开发状态: Preclinical
项目研究机构: Siegfried (Originator)
合成路线:The condensation of 7-(3-chloropropyl)theophylline (I) with 4-(p-fluorobenzoyl)piperidine (II) gives fluprofylline.
📌 参考资料/链接：
参考文献标题:Fluprofylline
文献作者:Jahn,U.; Thiele,K.
参考来源:Drugs Fut 1984,9(8),580
📄 详细内容
合成路线:The condensation of 7-(3-chloropropyl)theophylline (I) with 4-(p-fluorobenzoyl)piperidine (II) gives fluprofylline.
合成路线:The condensation of 7-(2-chloroethyl)theophylline (I) with 4-(p-fluorobenzoyl)piperidine (II) gives flufylline.
参考文献标题:Neue biologisch aktive Theophyllin-Derivate
文献作者:Thiele,K.; Geissmann,F.; Jahn,U.; Zimgibl,L.
参考来源:Arzneim-Forsch Drug Res 1984,34(1),1
合成路线:The condensation of 7-(3-chloropropyl)theophylline (I) with 4-(p-fluorobenzoyl)piperidine (II) gives fluprofylline.
合成路线:The condensation of 7-(2-chloroethyl)theophylline (I) with 4-(p-fluorobenzoyl)piperidine (II) gives flufylline.
参考文献标题:Theophylline derivatives
文献作者:Thiele,K.; Jahn,U.; Geissmann,F.; Zimgibl,L.
参考来源:ES 8304981; US 4603204; US 4668786; WO 8700841; ZA 8205123
产品链接: CAS No. 85118-43-0››