Letosteine
来托司坦Chemical Name: 2-[2-(2-Ethoxy-2-oxoethylsulfanyl)ethyl]thiazolidine-4-carboxylic acid
CAS No. 53943-88-7
项目整合开发状态: Not Determined
项目研究机构:
合成路线:The condensation of acrolein (I) with ethyl mercaptoacetate (II) by means of triethylamine in ether gives ethyl 3-oxopropylmercaptoacetate (III),which is then cyclized with cystein (IV) in ethanol - water.
📌 参考资料/链接：
参考文献标题:
文献作者:Chodkiewicz,M.X.
参考来源:BE 812653; DE 2410307; FR 2222087; GB 1452207; JP 74126666; JP 7741262; NL 7403785; US 4032534
📄 详细内容
合成路线:The condensation of acrolein (I) with ethyl mercaptoacetate (II) by means of triethylamine in ether gives ethyl 3-oxopropylmercaptoacetate (III),which is then cyclized with cystein (IV) in ethanol - water.
参考文献标题:Letosteine
文献作者:Blancafort,P.; Serradell,M.N.; Castar,J.; Neuman,M.
参考来源:Drugs Fut 1979,4(10),729
产品链接: CAS No. 53943-88-7››