Lestaurtinib, SPM-924, KT-5555, CEP-701
来他替尼Chemical Name: 9(S),12(R)-Epoxy-10(S)-hydroxy-10-(hydroxymethyl)-9-methyl-2,3,9,10,11,12-hexahydrodiindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocin-1-one
CAS No. 111358-88-4
项目整合开发状态: Phase II
项目研究机构: Kyowa Hakko (Originator), Cephalon (Licensee), Schwarz (Codevelopment), TAP (Codevelopment)
合成路线:The title compound was prepared by reduction of ester function of compound K-252 (I) by means of LiAlH4 in THF.
📌 参考资料/链接：
参考文献标题:Derivs.of physiologically active substance K-252
文献作者:Murakata,C.; Sato,A.; Takahashi,M.; Kobayashi,E.; Morimoto,M.; Akinaga,S.; Hirata,T.; Mochida,K.; Kase,H.; Yamada,K.; Iwahashi,K.(Kyowa Hakko Kogyo Co.,Ltd.)
参考来源:EP 0303697; WO 8807045