Timofibrate
替莫贝特Chemical Name: 3-[2-(4-Chlorophenoxy)-2-methylpropionyl]thiazolidine-4-carboxylic acid
CAS No. 64179-54-0
项目整合开发状态: Not Determined
项目研究机构:
合成路线:By reacting 2-(p-chlorophenoxy)-2-methylpropanoyl chloride (I) with thiazolidin-4-carboxylic acid (II) in water,in presence of NaOH.It combines in the same molecule,through amidation,a hepatotropic agent,thiazolidine carboxylic acid,with a classic hypolipemiant,clofibric acid.
📌 参考资料/链接：
参考文献标题:
文献作者:
参考来源:FR 2315271; IT 24693 A/75; JP 773060
📄 详细内容
合成路线:By reacting 2-(p-chlorophenoxy)-2-methylpropanoyl chloride (I) with thiazolidin-4-carboxylic acid (II) in water,in presence of NaOH.It combines in the same molecule,through amidation,a hepatotropic agent,thiazolidine carboxylic acid,with a classic hypolipemiant,clofibric acid.
参考文献标题:Timofribate
文献作者:Neuman,M.
参考来源:Drugs Fut 1978,3(11),844
产品链接: CAS No. 64179-54-0››