Tibolone, KB-889, Org-OD14, Xyvion, Boltin, Livial
替勃龙Chemical Name: 7alpha-Methyl-17alpha-ethynyl-17beta-hydroxy-19-norandrost-5(10)-en-3-one
CAS No. 5630-53-5
项目整合开发状态: Launched-1988
项目研究机构: Organon (Originator), Kanebo (Licensee)
合成路线:By condensation of 7-methyl-3,17,19-trioxo-DELTA4-androstene (I) with acetylene by means of potassium in liquid ammonia.
📌 参考资料/链接：
参考文献标题:Tibolone
文献作者:Castar,J.; Serradell,M.N.; Blancafort,P.; Hillier,K.
参考来源:Drugs Fut 1981,6(5),302
📄 详细内容
合成路线:By condensation of 7-methyl-3,17,19-trioxo-DELTA4-androstene (I) with acetylene by means of potassium in liquid ammonia.
参考文献标题:Process for the preparation of delta[5,(10)]-3-keto-19-nor-steroids
文献作者:Solomon,M.; Harryvan,E.A.
参考来源:BE 0700390; DE 1618747; FR 1527563; GB 1177845; US 3475465
产品链接: CAS No. 5630-53-5››