Trebenzomine, CI-686(hydrochloride)
曲苯佐明Chemical Name: 3,4-Dihydro-N,N,2-trimethyl-1-benzopyran-3-amine
CAS No. 23915-73-3
项目整合开发状态: Not Determined
项目研究机构:
合成路线:The reduction of 2-methyl-3-nitro-2H-1-benzopyran (I) with LiAlH4 in ether gives 2-methyl-3-chromanamine (II),which is then methylated by refluxing with a mixture of formaldehyde and formic acid,or by reaction with formaldehyde and hydrogen over Pd/C in water.
📌 参考资料/链接：
参考文献标题:
文献作者:Lockhart,J.M.
参考来源:DE 1919560; FR 2007481; GB 1151474; ZA 6902723
📄 详细内容
合成路线:The reduction of 2-methyl-3-nitro-2H-1-benzopyran (I) with LiAlH4 in ether gives 2-methyl-3-chromanamine (II),which is then methylated by refluxing with a mixture of formaldehyde and formic acid,or by reaction with formaldehyde and hydrogen over Pd/C in water.
参考文献标题:Trebenzomine
文献作者:Castar,J.; Owen,R.T.
参考来源:Drugs Fut 1978,3(7),556
产品链接: CAS No. 23915-73-3››