Tranilast, SB-252218, Rizaben
曲尼司特Chemical Name: N-(3',4'-Dimethoxycinnamoyl)anthranilic acid
CAS No. 53902-12-8
项目整合开发状态: Launched-1982
项目研究机构: Kissei (Originator), GlaxoSmithKline (Licensee)
合成路线:By condensation of anthranilic acid (o-aminobenzoic acid) (I) with 3,4-dimethoxycinnamoyl chloride (II) by means of pyridine in refluxing chloroform.
📌 参考资料/链接：
参考文献标题:N-5'
文献作者:Hillier,K.; Castar,J.
参考来源:Drugs Fut 1977,2(1),42
📄 详细内容
合成路线:By condensation of anthranilic acid (o-aminobenzoic acid) (I) with 3,4-dimethoxycinnamoyl chloride (II) by means of pyridine in refluxing chloroform.
参考文献标题:Aromatic carboxylic amide derivatives
文献作者:Harita,K.; et al.
参考来源:DE 2402398; FR 2214476; GB 1446141; JP 49093335; US 3940422
产品链接: CAS No. 53902-12-8››