Prifelone, S-16820, R-830T, R-830, Butafen
普立非酮Chemical Name: 2,6-Di-tert-butyl-4-(2'-thenoyl)phenol; [3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-thienylmethanone
CAS No. 69425-13-4
项目整合开发状态: Phase II
项目研究机构: 3M Pharmaceuticals (Originator)
合成路线:By a Friedel Kraft's condensation of 3,5-di-tert-butyl-4-hydroxybenzoyl chloride (I) with thiophene (II) by means of AlCl3 in refluxing carbon disulfide.
📌 参考资料/链接：
参考文献标题:R-830
文献作者:Arrigoni-Martelli,E.; Serradell,M.N.; Blancafort,P.; Castar,J.
参考来源:Drugs Fut 1983,8(10),867
📄 详细内容
合成路线:By a Friedel Kraft's condensation of 3,5-di-tert-butyl-4-hydroxybenzoyl chloride (I) with thiophene (II) by means of AlCl3 in refluxing carbon disulfide.
参考文献标题:
文献作者:Moore,G.G.I.
参考来源:US 4172082; US 4212882
产品链接: CAS No. 69425-13-4››