Antrafenine
安曲非宁Chemical Name: 2-[7-(Trifluoromethyl)quinolin-4-ylamino]benzoic acid 2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]ethyl ester
CAS No. 55300-29-3
项目整合开发状态: Not Determined
项目研究机构: Sanofi-Aventis (Originator)
合成路线:By transesterification of allyl 2-(7-trifluoromethyl-4-quinolinylamino)benzoate (I) with 2-[4-(m-trifluoromethylphenyl)-1-piperazinyl]ethanol (II) in refluxing toluene.
📌 参考资料/链接：
参考文献标题:Esters of 2-[(4-quinolyl)amino]benzoic acids
文献作者:Giudicelli,P.R.L.; et al.(Sanofi-Synthabo)
参考来源:DE 2415982; DE 2462460; GB 1441184; JP 50030891; US 3935229
📄 详细内容
合成路线:By transesterification of allyl 2-(7-trifluoromethyl-4-quinolinylamino)benzoate (I) with 2-[4-(m-trifluoromethylphenyl)-1-piperazinyl]ethanol (II) in refluxing toluene.
参考文献标题:Synthesis and analgesic activity of some anthranilic acid derivatives
文献作者:Manoury,Ph.; et al.
参考来源:5th Int Symp Med Chem 1976,Abst 074
合成路线:By transesterification of allyl 2-(7-trifluoromethyl-4-quinolinylamino)benzoate (I) with 2-[4-(m-trifluoromethylphenyl)-1-piperazinyl]ethanol (II) in refluxing toluene.
参考文献标题:Antrafenine
文献作者:Castar,J.; Blancafort,P.
参考来源:Drugs Fut 1977,2(12),786
产品链接: CAS No. 55300-29-3››