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项目整合精选>>>Amacetam hydrochloride(former USAN), Pramiracetam hydrochloride, CNS-1879, CI-879, Pramistar(sulfate), Neupramir(sulfate), Remen(sulfate)
Amacetam hydrochloride(former USAN), Pramiracetam hydrochloride, CNS-1879, CI-879, Pramistar(sulfate), Neupramir(sulfate), Remen(sulfate)
普拉西坦 硫酸普拉西坦Chemical Name: N-[2-(Diisopropylamino)ethyl]-2-oxo-1-pyrrolidineacetamide hydrochloride; N-[2-[Bis(1-methylethyl)amino]ethyl-2-oxo-1-pyrrolidineacetamide hydrochloride
CAS No. 75733-50-5, 68497-62-1 (free base), 72869-16-0 (sulfate)
项目整合开发状态: Launched-1993
项目研究机构: Pfizer (Originator), FIRMA (Licensee), Lusofarmaco (Licensee)
合成路线:By condensation of ethyl 2-oxo-1-pyrrolidineacetate (I) with 2-(diisopropylamino)ethylamine (II) at 100 C.
📌 参考资料/链接：
参考文献标题:N-(Substituted-aminoalkyl)-2-oxo-1-pyrrolidineacetamides
文献作者:L'Italien,Y.J.; Nordin,I.C.(Pfizer Inc.)
参考来源:BE 0864269; CA 1073457; DE 2808067; ES 467288; FR 2382441; GB 1588082; JP 53108966; US 4145347
📄 详细内容
合成路线:By condensation of ethyl 2-oxo-1-pyrrolidineacetate (I) with 2-(diisopropylamino)ethylamine (II) at 100 C.
参考文献标题:Pramiracetam Hydrochloride
文献作者:Castar,J.; Serradell,M.N.; Blancafort,P.
参考来源:Drugs Fut 1983,8(9),795