Oxatomide, KW-4354, R-35443, Tinset
奥沙米特Chemical Name: 1-[3-[4-(Diphenylmethyl)piperazin-1-yl]propyl]benzimidazol-2(3H)-one
CAS No. 60607-34-3
项目整合开发状态: Launched-1981
项目研究机构: Janssen (Originator), Formenti (Not Determined), Barrier Therapeutics (Formulation)
合成路线:By condensation of 4-diphenylmethylpiperazine (I) with 1-(3-chloropropyl)-2-benzimidazolone (II) by means of Na2CO3 in refluxing 4-methyl-2-pentanone.
📌 参考资料/链接：
参考文献标题:Oxatomide
文献作者:Church,M.K.; Castar,J.
参考来源:Drugs Fut 1978,3(6),465
📄 详细内容
合成路线:By condensation of 4-diphenylmethylpiperazine (I) with 1-(3-chloropropyl)-2-benzimidazolone (II) by means of Na2CO3 in refluxing 4-methyl-2-pentanone.
参考文献标题:Piperazine and piperidine derivative
文献作者:Yan,F.; et al.
参考来源:BE 0852405; JP 61005068; ZA 7702000
产品链接: CAS No. 60607-34-3››