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项目整合精选>>>Oxaprozin, Wy-21743, Xopane(as potassium), Daypro, Actirin, Alvo, Duraprox
Oxaprozin, Wy-21743, Xopane(as potassium), Daypro, Actirin, Alvo, Duraprox
奥沙普秦Chemical Name: 4,5-Diphenyl-2-oxazolepropanoic acid; beta-(4,5-Diphenyloxazol-2-yl)propionic acid
CAS No. 21256-18-8
项目整合开发状态: Launched-1983
项目研究机构: Wyeth Pharmaceuticals (Originator), Pfizer (Licensee)
合成路线:The condensation of benzoin (I) with succinic anhydride (II) by heating at 120 C gives benzoin hemisuccinate (III),which is cyclized with ammonium acetate in refluxing acetic acid.
📌 参考资料/链接：
参考文献标题:Oxazoles
文献作者:Brown,K.(Wyeth-Ayerst Laboratories)
参考来源:US 3578671
📄 详细内容
合成路线:The condensation of benzoin (I) with succinic anhydride (II) by heating at 120 C gives benzoin hemisuccinate (III),which is cyclized with ammonium acetate in refluxing acetic acid.
参考文献标题:Oxazoles
文献作者:Brown,K.(Wyeth-Ayerst Laboratories)
参考来源:GB 1206403; YU 244367; YU 249673
合成路线:The condensation of benzoin (I) with succinic anhydride (II) by heating at 120 C gives benzoin hemisuccinate (III),which is cyclized with ammonium acetate in refluxing acetic acid.
参考文献标题:Oxaprozin
文献作者:Arrigoni-Martelli,E.; Castar,J.
参考来源:Drugs Fut 1978,3(7),539
产品链接: CAS No. 21256-18-8››