Dinaline, PD-104208, NSC-328786, Goe-1734, AAPBA
地那林Chemical Name: 4-Amino-N-(2-aminophenyl)benzamide
CAS No. 58338-59-3
项目整合开发状态: Preclinical
项目研究机构: G鰀ecke (Originator), Pfizer (Originator)
合成路线:Condensation of 4-nitrobenzoyl chloride (I) with 2-nitrobenzenamine (II) in boiling dioxane yields N-(2-nitrophenyl)-4-nitrobenzamide (III),which is catalytically reduced by H2 over Pd/C in dimethylfomamide.
📌 参考资料/链接：
参考文献标题:N-Phenylbenzamide derivs.
文献作者:Herrmann,M.; Satzinger,G.; Fritschi,E.; Weierhausen,U.(G鰀ecke AG)
参考来源:EP 0116967; US 4816485
📄 详细内容
合成路线:Condensation of 4-nitrobenzoyl chloride (I) with 2-nitrobenzenamine (II) in boiling dioxane yields N-(2-nitrophenyl)-4-nitrobenzamide (III),which is catalytically reduced by H2 over Pd/C in dimethylfomamide.
参考文献标题:Dinaline
文献作者:Satzinger,G.; Weiershausen,U.
参考来源:Drugs Fut 1986,11(10),833
产品链接: CAS No. 58338-59-3››