Locicortolone dicibate, Locicortone, Ru-24643
地西洛可龙Chemical Name: (9alpha,11beta,16alpha)-9,11-Dichloro-21-(dicyclohexylmethoxycarbonyloxy)-16-methylpregna-1,4-diene-3,20-dione
CAS No. 78467-68-2
项目整合开发状态: Preclinical
项目研究机构: Aventis Pharma (Originator)
合成路线:By esterification of 9alpha,11alpha-dichloro-16alpha-methyl-21-hydroxy-pregna-1,4-dien-3,20-dione (I) with dicycloheylmethyl chloroformate (II) by means of pyridine in dioxane.
📌 参考资料/链接：
参考文献标题:Novel 16alpha-methylpregnane
文献作者:Teutsch,J.G.; Deraedt,R.(Aventis Pharma SA)
参考来源:DE 3028255; FR 2462443; GB 2054600; JP 56022798; US 4353899
📄 详细内容
合成路线:By esterification of 9alpha,11alpha-dichloro-16alpha-methyl-21-hydroxy-pregna-1,4-dien-3,20-dione (I) with dicycloheylmethyl chloroformate (II) by means of pyridine in dioxane.
参考文献标题:RU-24643
文献作者:Serradell,M.N.; Castar,J.
参考来源:Drugs Fut 1985,10(6),470
产品链接: CAS No. 78467-68-2››