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项目整合精选>>>Decitabine, Dezocitidine, AzadC, DAC, NSC-127716, Dacogen
Decitabine, Dezocitidine, AzadC, DAC, NSC-127716, Dacogen
地西他滨Chemical Name: 5-Aza-2'-deoxycytidine; 4-Amino-1-(2-deoxy-beta-D-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-one
CAS No. 2353-33-5
项目整合开发状态: Pre-Registered
项目研究机构: SuperGen (Orphan Drug), Pharmachemie (Originator), Cancer Research UK (Not Determined), National Cancer Institute (Not Determined), MGI (Licensee), SuperGen (Licensee), National Cancer Institute (Codevelopment)
合成路线:By condensation of silylated dihydro-s-triazine with deoxyribosyl chloride,catalyzed by SnCl4.
📌 参考资料/链接：
参考文献标题:Direct synthesis of 5-azapyridine 2'-deoxyribonucleosides.Hydrolysis of 5-aza-2'-deoxycytidine
文献作者:Piskala,A.; Synackova,M.; Tomankova,H.; Fiedler,P.; Zizkovsky
参考来源:Nucl Acid Res 1978,54109-13
📄 详细内容
合成路线:By condensation of silylated dihydro-s-triazine with deoxyribosyl chloride,catalyzed by SnCl4.
参考文献标题:DECITABINE
文献作者:Vrijhof,W.P.; De Vos,D.
参考来源:Drugs Fut 1990,15(1),19
产品链接: CAS No. 2353-33-5››