合成路线:1) The cyclization of 6-chloro-3-hydrazino-4-methylpyridazine (I) with refluxing formic acid gives 6-chloro-8-methyl-1,2,4-triazolo[4,3-b]pyridazine (II),which is then condensed with piperidine (III) at reflux temperature.
合成路线:2) By cyclization of 3-hydrazino-4-methyl-6-piperidinopyridazine (I) in refluxing formic acid.
参考文献标题:3,6,7,8-Substituted-s-triazolo[4,3-b]-pyridazines,their preparations and compositions comprising them
文献作者:Peet,N.P.; Sunder,S.(Aventis Pharmaceuticals,Inc.)
参考来源:EP 0029130; GB 2061275; JP 56079690
合成路线:1) The cyclization of 6-chloro-3-hydrazino-4-methylpyridazine (I) with refluxing formic acid gives 6-chloro-8-methyl-1,2,4-triazolo[4,3-b]pyridazine (II),which is then condensed with piperidine (III) at reflux temperature.
合成路线:2) By cyclization of 3-hydrazino-4-methyl-6-piperidinopyridazine (I) in refluxing formic acid.
参考文献标题:Zindotrine
文献作者:Castar,J.; Prous,J.
参考来源:Drugs Fut 1986,11(10),865
产品链接: CAS No. 56383-05-2››