Pirfenidone, S-7701, AMR-69, Deskar
吡非尼酮Chemical Name: 5-Methyl-1-phenylpyridin-2(1H)-one
CAS No. 53179-13-8
项目整合开发状态: Pre-Registered
项目研究机构: InterMune (Orphan Drug), Marnac (Originator), InterMune (Licensee), Shionogi (Licensee)
合成路线:By condensation of 5-methyl-2-(1H)-pyridone (I) with iodobenzene (II) by means of K2CO3 and Copper powder at reflux temperature.
📌 参考资料/链接：
参考文献标题:Pirfenidone
文献作者:Castar,J.; Blancafort,P.
参考来源:Drugs Fut 1977,2(6),396
📄 详细内容
合成路线:By condensation of 5-methyl-2-(1H)-pyridone (I) with iodobenzene (II) by means of K2CO3 and Copper powder at reflux temperature.
参考文献标题:N-Substituted pyridone and general method for preparing pyridones
文献作者:Gadekar,S.M.
参考来源:US 3839346; ZA 7309472
合成路线:By condensation of 5-methyl-2-(1H)-pyridone (I) with iodobenzene (II) by means of K2CO3 and Copper powder at reflux temperature.
参考文献标题:5-Methyl-1-phenyl-2-(1H)-pyridone compositions and methods of use
文献作者:Gadekar,S.M.
参考来源:CA 1049411; DE 2555411; US 3974281
产品链接: CAS No. 53179-13-8››