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项目整合精选>>>Diacetylrhein, Diacerhein, Diacerein, KW-4800, SF-277, Art 50, Fisiodar, Artrodar
Diacetylrhein, Diacerhein, Diacerein, KW-4800, SF-277, Art 50, Fisiodar, Artrodar
双醋瑞因; 二乙酰大黄酸; 二乙酰二氢蒽羧酸Chemical Name: 9,10-Dihydro-4,5-diacetoxy-9,10-dioxo-2-anthracenecarboxylic acid
CAS No. 13739-02-1
项目整合开发状态: Launched-1985
项目研究机构: Gentili (Originator), Proter (Originator), Takeda (Not Determined), Kyowa Hakko (Licensee), Negma (Licensee)
合成路线:Compound can be prepared in two different ways:1) By oxidation of acetylbarbaloin (II) with chromium trioxide.The acetylbarbaloin is obtained from barbaloin (I) with acetic anhydride.2) By acetylation of 1,8-dihydroxyanthraquinone-3-carboxylic acid (III) with sodium acetate and acetic anhydride.
📌 参考资料/链接：
参考文献标题:SF-277
文献作者:Neuman,M.
参考来源:Drugs Fut 1979,4(6),445
📄 详细内容
合成路线:Compound can be prepared in two different ways:1) By oxidation of acetylbarbaloin (II) with chromium trioxide.The acetylbarbaloin is obtained from barbaloin (I) with acetic anhydride.2) By acetylation of 1,8-dihydroxyanthraquinone-3-carboxylic acid (III) with sodium acetate and acetic anhydride.
参考文献标题:
文献作者:Robinson; Simonsen
参考来源:J Chem Soc 1909,1085
合成路线:Compound can be prepared in two different ways:1) By oxidation of acetylbarbaloin (II) with chromium trioxide.The acetylbarbaloin is obtained from barbaloin (I) with acetic anhydride.2) By acetylation of 1,8-dihydroxyanthraquinone-3-carboxylic acid (III) with sodium acetate and acetic anhydride.
参考文献标题:
文献作者:Oesterle
参考来源:Arch Pharm 1903,241607
合成路线:Compound can be prepared in two different ways:1) By oxidation of acetylbarbaloin (II) with chromium trioxide.The acetylbarbaloin is obtained from barbaloin (I) with acetic anhydride.2) By acetylation of 1,8-dihydroxyanthraquinone-3-carboxylic acid (III) with sodium acetate and acetic anhydride.
参考文献标题:Experiments on the constitution of the aloins.Part III
文献作者:Simonsen; Cahn
参考来源:J Chem Soc 1932,2573
产品链接: CAS No. 13739-02-1››