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项目整合精选>>>Carboplatin, NSC-241240, JM-8, CBDCA, Ercar, Paraplatin
Carboplatin, NSC-241240, JM-8, CBDCA, Ercar, Paraplatin
卡铂Chemical Name: cis-Diammine(1,1-cyclobutanedicarboxylato)platinum
CAS No. 41575-94-4
项目整合开发状态: Launched-1986
项目研究机构: Bristol-Myers Squibb (Originator), Johnson Matthey (Originator), American Pharmaceutical Partners (Not Determined), National Cancer Institute (Not Determined), Almirall Prodesfarma (Licensee)
合成路线:The reaction of cis-diammine-platinum diiodide (I) with silver sulfate (II) gives cis-diaquo-diammine-platinum sulfate (III),which is then treated with barium cyclobutane-1,1-dicarboxylate (IV).
📌 参考资料/链接：
参考文献标题:Carboplatin
文献作者:Serradell,M.N.; Blancafort,P.; Castar,J.; Hopkins,S.J.
参考来源:Drugs Fut 1983,8(6),489
📄 详细内容
合成路线:The reaction of cis-diammine-platinum diiodide (I) with silver sulfate (II) gives cis-diaquo-diammine-platinum sulfate (III),which is then treated with barium cyclobutane-1,1-dicarboxylate (IV).
参考文献标题:An efficient route for the preparation of highly soluble platinum (II) antitumor agents
文献作者:Zaki,A.M.; Harrison,R.C,McAuliffe,C.M.
参考来源:Inorg Chim Acta 1980,46(1),L15-16
产品链接: CAS No. 41575-94-4››