Pivagabine, Tonerg
匹伐加宾Chemical Name: 4-Pivalamidobutyric acid; 4-(2,2-Dimethylpropionamido)butanoic acid
CAS No. 69542-93-4
项目整合开发状态: Withdrawn
项目研究机构: Angelini (Originator)
合成路线:Pivagabine is prepared by reacting pivaloyl chloride (I) and 4-aminobutyric acid (II) in aqueous sodium hydroxide solution; by adding dilute hydrochloric acid the crude product is isolated and then purified by crystallization from water.
📌 参考资料/链接：
参考文献标题:Pivagabine
文献作者:Esposito,G.; Lazzarini,R.
参考来源:Drugs Fut 1998,23(4),390
📄 详细内容
合成路线:Pivagabine is prepared by reacting pivaloyl chloride (I) and 4-aminobutyric acid (II) in aqueous sodium hydroxide solution; by adding dilute hydrochloric acid the crude product is isolated and then purified by crystallization from water.
参考文献标题:Adjustment disorder as a marginal or transitional illness category in DSM-III
文献作者:Mezzich,J.E.; Mezzich,A.C.; Fabrega,H.
参考来源:Arch Gen Psychiatry 1987,44(6),567-72
产品链接: CAS No. 69542-93-4››