Riodipine, PP-1466, Foridone, Phoridone
利奥地平Chemical Name: 4-[2-(Difluoromethoxy)phenyl]-1,4-dihydro-2,6-dimethyl-3,5-pyridinecarboxylic acid dimethyl ester; Dimethyl 4-[o-(difluoromethoxy)phenyl]-1,4-dihydro-2,6-dimethy-3,5-pyridinedicarboxylate; 2,6-Dimethyl-3,5-dimethoxycarbonyl-4-(o-difluoromethoxyphenyl)-1,4-dihydropyridine
CAS No. 71653-63-9
项目整合开发状态: Phase II
项目研究机构: Latvian Institute of Organic Synthesis (Originator), Nikken Chemicals (Originator)
合成路线:By cyclization of 2-(difluoromethoxy)benzaldehyde (I) with methyl acetoacetate (II) and refluxing aqueous concentrated ammonia.
📌 参考资料/链接：
参考文献标题:2,6-Dimethyl-3,5-dimethoxycarbonyl-4-(o-difluoromethoxyphenyl)1,4-dihydropyridine
文献作者:Dubur,G.Y.
参考来源:DE 2900537; FR 2414501; GB 2013186; JP 79122280; US 4219653
📄 详细内容
合成路线:By cyclization of 2-(difluoromethoxy)benzaldehyde (I) with methyl acetoacetate (II) and refluxing aqueous concentrated ammonia.
参考文献标题:Riodipine
文献作者:Serradell,M.N.; Castar,J.
参考来源:Drugs Fut 1985,10(11),922
产品链接: CAS No. 71653-63-9››